Senior/Staff Software Engineer

Home > Python programming jobs

Senior/Staff Software Engineer in USA

Merge Labs
Full time
Email

USA
10/09/2026
Report

San Francisco, CA

Responsibilities

Own important software through problem definition, implementation, deployment, and continued operation.
Translate experimental needs into achievable software milestones with clear acceptance criteria.
Build and improve interfaces between applications, instrument SDKs, data systems, and infrastructure.
Solve integration, concurrency, performance, and recovery problems with SDK and application engineers.
Make decisions about languages, architecture, reuse, and build-versus-buy tradeoffs.
Establish testing, observability, and release practices that improve reliability and research velocity.
Build workflows for recording, storing, managing metadata for, and analyzing high-volume experimental data.
Review code, mentor peers, communicate technical tradeoffs, and help prioritize work with the team manager.

Requirements

Demonstrated delivery and post-release support of substantial software systems.
Strong coding, debugging, and software fundamentals with the ability to learn unfamiliar technologies.
Experience making architecture decisions across multiple components and explaining simplifications and tradeoffs.
Good judgment regarding reliability, data integrity, performance, and operational failure modes.
Evidence of helping other engineers deliver through code review, mentoring, and collaboration.
Helpful but not required: experience with scientific software, robotics, instrumentation, imaging, lab automation, physical systems, Python, C++, Rust, Matlab, scientific data pipelines, high-throughput systems, or desktop applications.
Previous people management experience or interest in developing people-management skills is helpful but not required.

Salary: $225k - $305k/yr

Merge Labs

Merge Labs is a research lab with the long-term mission of bridging biological and artificial intelligence to maximize human ability, agency and experience. Join us: merge.io/careers

Similar positions

Staff Machine Learning Engineer

Altana
Full time

USA
10/15/2026
Salary: $205k - $240k/yr

Boston, MA

Security Platform Automation Engineer

Apple
Full time

USA
10/15/2026

Seattle, WA

Analytics Engineer

Reddit
Full time

USA
10/15/2026
Salary: $164k-$230k

Remote

Senior AI Engineer

Infiterra S.A
Full time

Remote
10/15/2026

Greece, UK

Security Operations Engineer (SecOps)

Collibra
Full time

USA
10/15/2026
Salary: $116k - $145k/yr

Remote