OpenEvidence builds an AI-powered medical information and clinical decision-support platform for clinicians and healthcare organizations, combining search across guidelines, clinical trials, and journals. The product is delivered as cloud-based software and used to retrieve evidence and literature at the point of care. Founded in 2021 and headquartered in Miami, it emerged from the Mayo Clinic Platform Accelerate program and partners with NEJM and JAMA, with backing from Sequoia and Google.