Flagship Pioneering invents, builds, and finances platform biotechnology companies in human health and sustainability, providing founding science, capital, and operational support to entrepreneurs and researchers. The privately held firm, founded in 2000 and headquartered in Cambridge, MA, has originated more than 100 ventures and maintains an ecosystem of 40+ companies. Notable portfolio companies include Moderna, Denali Therapeutics, Generate:Biomedicines, Indigo Agriculture, and Tessera Therapeutics.